Dr. D'Souza is a Professor and Research Director for the Dental Branch, Department of Orthodontics and is involved in __________________.

Education:

Ph.D. 1987 - University of Texas, Houston, Texas

D.D.S. 1985 - University of Texas Dental Branch at Houston, Texas

M.S. 1985 - University of Texas, Houston, Texas

B.D.S. 1977 - University of Bombay, India

Genetic Control of Odontoblast Differentiation and  Function; signaling interactions in tooth development; mouse models of human genetic disorders affecting the craniofacial complex.

Research

Principal Investigator on NIH Grants
          R29 DE10517 (1992-1998)
          RO3 DE12269 (1997-1999)
          RO1 DE11663 (1997-2001)

Teaching

Course Coordinator (co-director):  DBPG 0918 Graduate Oral Biology 2
Course Coordinator (co-director):  GS21 0082 Oral Biomaterials
Lecturer:  DENS 1503 Oral Histology and Embryology
          Tooth Development, Enamel, Dentin, Pulp, Repair and Regeneration
Lecturer:  DBPG 0918 Graduate Oral Biology 2
          Signaling molecules in odontogenesis; amelogenesis and enamel
Lecturer:  GS21 0082 Oral Biomaterials
          Bioactive mat4erials for oral tissue regeneration

Publications (five most important)

• Stashenko P, Teles R and D'Souza R (1998).  Periapical inflammatory response and their modulation.  Critical Reviews in Oral Biology & Medicine, May.
• D'Souza RN, Cavender A, Sunavala G, Alvarez J, Ohshima T, Kulkarni AB and MacDougall M (1997).  Gene expression patterns of murine dentin matrix protein 1 and dentinsialophosphoprotein suggest distinct developmental functions In Vivo.  J Bone Min Res, 12(12), 1-10.
• D'Souza RN and Litz M (1995).  Analysis of tooth development in mice bearing a TGF-b1 1 null mutation.  Conn Tissue Res, 32(1), 41-46.
• D'Souza RN, Niederreither K and de Crombrugghe B (1993).  Osteoblast-specific expression of the pro 2(I) collagen promoter in transgenic mice: Correlation with the distribution of TGF-b1.  J Bone and Min Res, 8(9), 1127-1136.
• D'Souza RN, Bronckers ALJJ, Happonen R-P, Doga DA, Farach-Carson MC and Butler WT (1992).  Developmental expression of a 53 KD dentin sialoprotein in rat tooth organs", J Histochem Cytochem 40(3), 359-366.