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M. John Hicks
Professor
of Pathology
|
Education/Training
|
Institution |
Degree |
Year Conferred |
Field of Study |
| University of Iowa, Iowa City IA |
B.S. |
1973 |
Pre-Dentistry |
| University of Iowa, Iowa City IA |
D.D.S. |
1976 |
Dentistry |
| University of Iowa, Iowa City IA |
M.S. |
1978 |
Pediatric Dentistry |
| University of Iowa, Iowa City IA |
Ph.D. |
1982 |
Anatomy |
| University of Miami, Miami FL |
Ph.D. |
1998 |
Medicine |
Positions:
| 1993-present |
Associate Professor, Medical Director
of Surgical and Ultrastructural Pathology, Renal Pathology and Oncologic
Pathology, Department of Pathology, Baylor College of Medicine,
Houston TX |
| 1990-present |
Adjunct Professor, Department of Pediatric Dentistry,
Univ of Texas-Dental Branch , Houston TX |
| 1992-1993 |
Surgical Pathology Fellow and Chief Fellow, MD
Anderson Cancer Ctr, Houston TX |
| 1990-1992 |
Anatomic Pathology Resident and Chief Resident,
Baylor College of Medicine, Houston TX |
| 1989-1990 |
Anatomic Pathology Resident, School of Medicine,
University of Colorado, Denver CO |
| 1988-1989 |
Transitional Internship, Presbyterian/St. Luke’s
Medical Center, Denver CO |
| 1983-86 |
Associate Professor, Dept of Growth and Development,
Univ of Colorado School of Dentistry, Denver, CO |
| 1973-1983 |
Adjunct Assistant Professor, Div of Cariology,
Dows Inst for Dental Research, Univ of Iowa, Iowa City IA |
| 2002-2004 |
President-Elect, Society for Ultrastructural
Pathology |
| 1996-2008 |
Executive Council Member, Socitey for Ultrastructural
Pathology |
| 2000-2003 |
Practice Committee, Society for Pediatric Pathology |
| 2003-2006 |
Research Committee, Society for Pediatric Pathology |
Editorial Boards:
| Sept 2000-present |
Ultrastructural Pathology,
Society for Ultrastructural Pathology |
| Jan 2000-present |
Journal of Dentistry for Children, American
Society of Dentistry for Children |
| Jan 2000-present |
American Journal of Dentistry |
| May 1997-present & 1985-1986 |
Pediatric Dentistry, American Academy
of Pediatric Dentistry |
| May 1994 -present |
Oral Surgery, Oral Medicine, Oral Pathology,
Oral Radiology, Endodontics, Mosby-YearBook Publishers, |
| Jan 2000-present. |
American Journal of Dentistry |
Honors and Awards:
| 2003, 2000, 1999, 1998, 1997, 1996,
1995, 1994, 1993 |
Educational Foundation Research Award,
American Academy of Pediatric Dentistry. |
| March 2002 |
O’Neal/Spjut Award in Anatomic Pathology
for 2001, Department of Pathology, Baylor College of Medicine, Houston. |
| 2001 |
George W. Teuscher Silver Pen Award for 2001 (inaugural
award), American Society of Dentistry for Children, Journalism Award
for Best Paper |
| 2002 |
Harry B. Neustein Award, Society for Pediatric
Pathology |
| 1999, 1997, 1995, 1985 |
Journalism Award, American Society of Dentistry
for Children Foundation |
| 1999 |
Microscopy Society of America Council Award, First
Place |
Selected Peer-reviewed Publications (in chronological
order):
1. Lau CC, Harris CP, Lu XY, Perlaky L, Gogineni
S, Chintagumapala M, Hicks J, et al: Frequent amplification and rearrangement
of chromosomal bands 6p12-21 and 17p11.2 in osteosarcoma. Genes Chromosomes
Cancer 2004;39(1):11-21.
2. Wu J, Borillo J, Glass WF, Hicks J, Ou CN, Lou YH: T-cell epitope
of alpha3 chain of type IV collagen induces severe glomerulonephritis.
Kidney Int 2003;64(4): 1292-1301.
3. Wang H, Hicks J, Khanbolooki P, Kim SJ, Yan C, Wang Y, Boyd D:
Transgenic mice demonstrate novel promoter regions for tissue specific
expression of urokinase receptor gene. Am J Pathol 2003;163(2):453-64.
4. Hicks J, Garcia-Godoy F, Flaitz C: Biologic factors I dental caries:
role of saliva and dental plaque in the dynamic process of demineralization
and remineralization (part 1). J Clin Pediatr Dent 2003;28(1):47-52.
5. Flaitz C, Allen C, Neville B, Hicks J: Juvenile xanthogranuloma
of the oral cavity in children: a clinicopathologic study. Oral Surgery,
Oral Medicine, Oral Pathology, Oral Radiology, Endodontics 2002;94(3):345-52.
6. Hicks J, Flaitz C: Progressive transformation of germinal centers:
review of histopathologic and clinical features. International Journal
of Otorhinolaryngology 2002;65(3):195-202.
7. Flaitz CM, Nichols CM, Walling DM, Hicks MJ: Plasmablastic lymphoma:
an HIV-associated entity with primary oral manifestations. Oral Oncology
2002;38(1):95-102.
8. Dickinson DP, Thiesse M, Hicks J: Expression of type 2 cystatin
genes CST1-CST5 in adult human tissues and developing submandibular
glands. DNA Cell Biol 2002 Jan;21(1):47-65.
9. Holsinger FC, Weeks BH, Hicks MJ, Friedman EM: Contemporary concepts
in the management of pediatric rhabdomyosarcoma. Current Opinion in
Otolaryngology & Head and Neck Surgery 2002;10:91-96.
10. Flaitz CM, Hicks MJ: Mucocele and ranula. http://www.emedicine.com/emerg/topic
169.htm, eMedicine Journal, 2002;3(3):1-10.
11. Hicks J, Flaitz C: Rhabdomyosarcoma of the head and neck in children.
Oral Oncol 2002;38(5): 450-459, August.
12. Hicks J: Congenital self-healing Langerhans cell histiocytosis:
complimentary role of immunocytochemical and ultrastructural evaluation.
Pathology Case Reviews 2002;7(5):209-17, August-September
13. Wu J, Hicks J, Ou C, Singleton D, Borillo J, Lou YH: Glomerulonephritis
induced by recombinant collagen IV alpha 3 chain noncollagen domain
1 is not associated with glomerular basement membrane antibody: a
potential T cell-mediated mechanism. J Immunol 2001;167(4):2388-95.
14. Flaitz CM, Hicks MJ: Pulp Polyp. http://www.emedicine.com/emerg/topic
169.htm eMedicine Journal 2001;2(9):1-8.
15. Stal S, Tjelmeland K, Hicks J, Bhatia N, Eppley B, Hollier L:
Compartmentalized bone regeneration of cranial defects with biodegradable
barriers: an animal model. J Craniofac Surg 2001;12(1):41-7.
16. Flaitz CM, Wullbrandt B, Sexton J, Bourdon T, Hicks J: Prevalence
of orodental findings in HIV-infected Romanian children. Pediatr Dent
2001;23(1):44-50.
17. Hicks J, Wild T, Flaitz C, Seybold S: Fluoride varnishes and caries
development in primary tooth enamel: an in vitro study. ASDC J Dent
Child 2001;68(5&6):304-10, Sept-Dec.
18. Agostini FG, Flaitz CM, Hicks MJ: A retrospective survey of dental
emergencies in a university- based pediatric dental clinic. ASDC J
Dent Child 2001;68(5&6):316-21.
19. Flaitz CM, Hicks J: Delayed tooth eruption associated with ameloblastic
fibro-odontoma. Pediatr Dent 2001;23(3):253-4.
20. Hicks MJ, Flaitz CM: External root resorption of a primary molar:
“incidental” histopathologic finding of clinical significance.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2001;92(1):4-8.
21. Hicks MJ, Parkins FM, Flaitz CM: Kinetic cavity preparation effects
on secondary caries formation around resin restorations: a polarized
light microscopic in vitro evaluation. ASDC J Dent Child 2001;68(2):115-21,80,142.
22. Westerman G, Hicks J, Flaitz C: Argon laser curing of fluoride
releasing pit and fissure sealant: in vitro caries development. ASDC
J Dent Child 2001;67(6):385-90,374.
23. Hicks J, Garcia-Godoy F, Milano M, Flaitz CM: Compomer materials
and secondary caries formation. Am J Dent 2001;13(5):231-4.
24. Ceballos L, Toledano M, OsorioR, Garcia-Godoy F, Flaitz C, Hicks
J: Er-YAG laser pretreatment effect on in vitro secondary caries formation
around composite restorations. Am J Dent 2001;14(1):46-9.
25. Hicks MJ, Flaitz CM: Oral mucosal melanoma: epidemiology and pathobiology.
Oral Oncology 2000;36:152-69.
26. Hicks J, Flaitz C: Mucoepidermoid carcinoma of salivary glands
in children and adolescents: assessment of proliferation markers.
Oral Oncol 2000;36(5):454-60.
27. Kozinetz CA, Carter AB, Simon C, Hicks MJ, Rossmann SN, Flaitz
CM, Cron SG, Kline MW: Oral manifestations of pediatric vertical HIV
infection. AIDS Patient Care STDS. 2000;14:89-94.
28. Hicks MJ, Flaitz CM, Carter AB, Cron SG, Rossmann SN, Simon CL,
Demmler GJ, Kline MW: Dental caries in HIV-infected children: a longitudinal
study. Pediatr Dent 2000;22(5):359-64.
29. Hicks MJ, Flaitz CM: Resin-modified glass ionomer restorations
and in vitro secondary caries formation in coronal enamel. Quintessence
International, 2000;31(8):570-8.
30. Hicks MJ, Westerman GH, Flaitz CM, Powell GL: Surface topography
and enamel-resin interface of pit and fissure sealants following visible
light and argon laser polymerization: an in vitro study. ASDC J Dent
Child 2000;67:169-75.
31. Hicks MJ, Flaitz CM: Enamel caries formation and lesion progression
with a fluoride dentifrice and a calcium-phosphate containing fluoride
dentrifrice: a polarized light microscopic study. ASDC J Dent Child
2000;67:21-8.
32. Hicks MJ, Flaitz CM, Garcia-Godoy F: Fluoride-releasing sealant
and caries-like enamel lesion formation in vitro. J Clin Pediatr Dent.
2000;24(3):215-19.
33. Hicks MJ, Flaitz CM: Occlusal caries formation in vitro: comparison
of resin-modified glass ionomer with fluoride-releasing sealant. J
Clin Pediatr Dent 2000;24(4):309-14.
34. Simon C, Hicks MJ (shares first co-authorship with C Simon), Nemechek
AJ, O’Malley Jr BW, Goepfert H, Flaitz CM, Boyd D: PD08059,
an inhibitor of ERK1 activation, attentuates the in vivo invasiveness
of head and neck squamous cell carcinoma. Br J Cancer 1999;80(9):1412-9.
35. Flaitz CM, Hicks MJ: Oral candidiasis in children with immune
suppression: clinical appearance and therapeutic considerations. ASDC
J Dent Child 1999;66(3):161-6,154.
36. Westerman GH, Hicks MJ, Flaitz CM, Blankenau RJ, Powell GL: Combined
effects of acidulated phosphate fluoride and argon laser on sound
root surface morphology; an in vitro scanning electron microscopic
study. J Clin Laser Med Surg 1999;17:63-8
37. Flaitz C.M., Hicks MJ: Molecular piracy: the viral link to carcinogenesis.
Oral Oncol 1998;34(6):448 53.
38. Simon C, Nemechek AJ, Boyd D, O’Malley BW Jr, Goepfert H,
Flaitz CM, Hicks MJ: An orthotopic floor-o-mouth cancer model allows
quantification of tumor invasion. Laryngoscope 1998;108(11 Pt1):1686-91.
39. Garcia-Godoy F, Flaitz CM, Hicks J: Secondary caries adjacent
to amalgam restorations lined with a fluoridated dentin desensitizer.
Am J Dent 1998;11(6):254-8.
40. Stal S, Hicks MJ: Classic and occult submucous cleft palates:
a histopathologic analysis. Cleft Palate Craniofac J 1998;35(4):351-8.
41. Khadaroo RG, Walton RJ, Ramsay JA, Hicks MJ, Archibald SD: Mucoepidermoid
carcinoma of the parotid gland: a rare presentation in a young child.
J Pediatr Surg 1998;33(6):893-5.
42. Hicks MJ, Carter AB, Rossmann SN, Demmler GJ, Simon CL, Cron SG,
Flaitz CM, Shearer WT, Kline MW: Detection of fungal organisms in
saliva from HIV-infected children: a preliminary cytologic analysis.
Pediatric Dentistry 1998;20(3):162-8.
43. Flaitz CM, Hicks MJ, Carter AB, Rossmann SN, Demmler GJ, Simon
CL, Cron SG, Shearer WT, Kline MW: Saliva collection technique for
cytologic, microbiologic and viral evaluation in pediatric HIV infection.
ASDC J Dent Child 1998;65(5);318-24,355.
44. Hicks MJ, Flaitz CM: Caries formation in vitro around a fluoride-releasing
pit and fissure sealant in primary teeth. ASDC J Dent Child 1998;65(3):161-8
45. Hicks MJ, Flaitz CM, Garcia-Godoy F: Root surface caries formation:
Effect in vitro APF Treatment. J Am Dent Assoc 1998;129(4):449-53.
46. Rossmann S, Wilson P, Hicks J, Carter B, Crons S, Flaitz C, Demmler
G, Shearer W, Kline M: Lautropic mirabilis is associated with HIV
in the oral cavities of children. J Clin Microbiol 1998;36(6):1756-60.
47. Jacob LS, Flaitz CM, Nichols CM, Hicks MJ: Role of dentinal carious
lesions in the pathogenesis of oral candidiasis in HIV infection.
J Am Dent Assoc. 1998;129(2):187-94.
48. Westerman GH, Hicks MJ, Flaitz CM, Blankenau RL, Powell GL: Argon
laser irradiation effects on sound root surfaces: in vitro scanning
electron microscopic observations. J Clin Laser Med Surg. 1998(2);16:111-5.
49. Hicks, M.J., Flaitz, C.M., Cohen, P.R.: Perioral and Cutaneous
Umbilicated Papular Lesions in Acquired Immunodeficiency Syndrome.
Oral Surgery, Oral Medicine, Oral Pathology, Endodontics. 1997:83:189-91.
50. Flaitz C.M., Jin Y.T., Hicks M.J., Nichols C.M., Wang Y-W, Su
I-J: Kaposi’s sarcoma-associated Herpesvirus-like DNA Sequences
(KSHV/HHV-8) in oral AIDS-Kaposi’s Sarcoma. Oral Surgery, Oral
Medicine, Oral Pathology, Endodontics 1997;83:259-64.
Research Support
1. Molecular Classification of Osteosarcoma, NIH-NCI
Director’s Challenge Grant, Principal Investigator (Ching Lau),
February 2001 to February 2006 ($5.2 million). 10% effort.
2. Oral Manifestations of Pediatric HIV Infection, NIH-NIDR, (1-RO1-DE11363),
September 1994 to September 1999, Co-Investigator. (Dr. Mark Kline,
Principal Investigator, $1.2 million). 10% effort.
3. The Effects of Normal Aging Process on the Larynx. Isla Carroll
Turner Friendship Trust. July 1995 to July 2000, Co-Investigator.
(Dr. C. Richard Stasney, co-investigator, $160,000). 20% effort
4. Design for a Mouse Model of Langerhans Cell Histiocytosis. Histiocyte
Association of America. Co-investigtor (Dr. Kenneth McClain, Co-Investigator,
$50,000). June 2001. 5% effort Consultant (Collaborator)
1. Molecular Basis of Rothmund-Thomson Syndrome, Principal Investigator:
Lisa Wang, NIH-NCI KO8 Grant and Doris Duke Charitable Foundation
Clinical Scientist Development Award, February 2002-February 2007
($500,000). 5% effort
2. Urokinase Receptor Regulation in Transgenic Mice, Principal Investigator:
Douglas Boyd, NIH, 2001 ($1.2 million). 5% effort
3. Role of P and E-selectin in the Development of Vasculitis, Investigator:
Daniel Bullard, Arthritis Foundation of America, April 2000 ($50,000).
4. Role of Selectins in the Development of Vasculitis, Investigator:
Daniel Bullard, Arthritis Foundation of America, January 1999 ($50,000).
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